Pharmaceutical plants handle active ingredients and excipients that must be blended, granulated, dried, sized and coated without contamination or loss of uniformity. Equipment has to be cleanable between batches, built from suitable contact materials and documented for validation.
We build machines for oral solid dosage (tablets and capsules), liquid orals, ointments and creams, and for bulk drug and intermediate processing.
Process challenges
Blend uniformity: low-dose actives must be spread evenly through the batch, without segregation during discharge.
Cleaning and changeover: product contact parts must be easy to dismantle, inspect and clean between products.
Heat-sensitive and solvent-wet material: drying must be gentle and controlled, often under vacuum.
Dust and containment: fine powders need closed transfer and dust collection to protect operators and the product.
How we solve them
We supply the main equipment for each step of granulation and liquid preparation: mass mixers, double cone blenders and ribbon blenders for mixing and lubrication, multi mills for sizing, fluid bed dryers and tray dryers for drying, vibro sifters for screening and coating pans. For liquids and semi-solids we build preparation vessels and syrup plants, ointment and cream plants and homogenizers.
Contact parts can be built in SS 316 / 316L with polished finishes, and machines are configured to your batch size and room layout.
Typical process flow
Dispensing and sifting
Raw materials are weighed and sifted to remove lumps and foreign matter.
Mixing and granulation
Powders are dry-mixed, then wet-massed with binder in a mass mixer.
Drying and sizing
Wet granules are dried in a fluid bed or tray dryer and sized in a multi mill.
Blending and coating
Granules are lubricated in a blender, compressed, then coated in a coating pan.
